久久精品国产福利电影网-久久精品国产eeuss-久久精品国产99欧美精品亚洲-久久精品国产96精品亚洲-一区两区三不卡-一区精品在线

咨詢熱線

15336881895

當前位置:首頁  >  技術文章  >  Cell stretching systems : Cyclic stretching helps cells grow

Cell stretching systems : Cyclic stretching helps cells grow

更新時間:2023-02-09      點擊次數:1215

40389534_副本.jpg

Mechanical stretching is experienced ubiquitously by human tissues and their constituent cells and impacts biochemical and (mechano)biological processes relevant to health and disease. Numerous cell-stretching systems (CSSs) have been developed and used to apply mechanical strain to cells and tissues in in-vitro settings.

Mammalian cells in-vivo are constantly sensing and responding to the mechanical forces originating from adjacent cells, their environment, and to the changing properties of their extracellular matrix (ECM). Many physiological functions such as breathing, digestion, muscle contraction, heartbeat, and brain development entail cells being constantly stretched and/or compressed.

A central element in these processes is the ability of cells to sense these mechanical forces (mechanosensing) and transduce mechanical information as a response (mechanotransduction).

1-s2.0-S0167779922003328-gr2_lrg.jpg

Since mechanical stretch (MS) is ubiquitous in tissues and constituent cells, it is critical to account for it during experimentation in-vitro. To uncover the spatiotemporal alterations that occur at the cellular and molecular scale during MS, CSSs are utilized that allow application of MS to multicellular assemblies.

CSSs for the study of biological responses of multicellular assemblies to MS have been used in research laboratories for decades.

Depending on the biological questions posed, several parameters need to be considered in terms of CSS design, capabilities, and automation, including: (i) compatibility with high-resolution live-cell imaging modalities; (ii) compatibility with specific assays; (iii) compatibility with (bio)mechanical characterization methods; (iv) biomimetic abilities; and (v) possibility of simultaneously integrating other physical cues.

CELL&FORCE offers three main CSSs: devices that allow high-throughput long-term uniaxial (CellTank) or biaxial (Biaxialler) stretching and devices that are microscope-mountable for live-cell imaging (Beatle).

● Max velocity up to 30 mm/s

● Frequency ranges from 0.01-5 Hz

● Ability to program multiple frequency, amplitude and wave changes

● Waveforms available: Static/Sinusoidal/Triangular/Square Heart wave and custom

主站蜘蛛池模板: 人妖xxhdxx | 二次元美女扒开内裤喷水 | free俄罗斯性xxxxhd派对 | 亚洲 综合 自拍 精品 在线 | 秋霞电影网视频一区二区三区 | 亚洲无遮挡无码A片在线 | 夫妻性姿势真人做视频 | 欧美亚洲韩日午夜 | 欧美性动漫3d在线观看完整版 | 火影小南被爆羞羞网站 | 亚洲欧美国产综合在线一区 | 蛇缚dvd| 浴室里强摁做开腿呻吟的漫画男男 | 亚洲免费人成 久久 | 狠狠狠色丁香婷婷综合久久 | 人人射人人爱 | babesvideos性欧美| 国产在线视频分类精品 | 一区二区三区国产 | 草民电影网午夜伦理电影网 | 久久伊人影视 | 我们中文在线观看免费完整版 | 一一本之道高清视频在线观看中文字幕 | 红桃视频国产AV | 欧美另类极品videosbest | 午夜福利视频极品国产83 | 国产在线视频分类精品 | 亚洲电影第1页 | 国产成人免费网站在线观看 | 岛国片免费在线观看 | 国产亚洲欧美日韩综合综合二区 | 亚洲an天堂an在线观看 | 99国产精品偷窥熟女精品视频 | 国产午夜精品久久理论片小说 | 日本一区不卡在线播放视频免费 | 伊人久久大香线蕉综合99 | 德国美女密密麻麻浓毛 | 无限资源在线观看高清 | 午夜理论在线观看不卡大地影院 | 日本午夜精品理论片A级APP发布 | 热综合一本伊人久久精品 |