久久精品国产福利电影网-久久精品国产eeuss-久久精品国产99欧美精品亚洲-久久精品国产96精品亚洲-一区两区三不卡-一区精品在线

咨詢熱線

15336881895

當前位置:首頁  >  技術文章  >  Cell stretching systems : Cyclic stretching helps cells grow

Cell stretching systems : Cyclic stretching helps cells grow

更新時間:2023-02-09      點擊次數:967

40389534_副本.jpg

Mechanical stretching is experienced ubiquitously by human tissues and their constituent cells and impacts biochemical and (mechano)biological processes relevant to health and disease. Numerous cell-stretching systems (CSSs) have been developed and used to apply mechanical strain to cells and tissues in in-vitro settings.

Mammalian cells in-vivo are constantly sensing and responding to the mechanical forces originating from adjacent cells, their environment, and to the changing properties of their extracellular matrix (ECM). Many physiological functions such as breathing, digestion, muscle contraction, heartbeat, and brain development entail cells being constantly stretched and/or compressed.

A central element in these processes is the ability of cells to sense these mechanical forces (mechanosensing) and transduce mechanical information as a response (mechanotransduction).

1-s2.0-S0167779922003328-gr2_lrg.jpg

Since mechanical stretch (MS) is ubiquitous in tissues and constituent cells, it is critical to account for it during experimentation in-vitro. To uncover the spatiotemporal alterations that occur at the cellular and molecular scale during MS, CSSs are utilized that allow application of MS to multicellular assemblies.

CSSs for the study of biological responses of multicellular assemblies to MS have been used in research laboratories for decades.

Depending on the biological questions posed, several parameters need to be considered in terms of CSS design, capabilities, and automation, including: (i) compatibility with high-resolution live-cell imaging modalities; (ii) compatibility with specific assays; (iii) compatibility with (bio)mechanical characterization methods; (iv) biomimetic abilities; and (v) possibility of simultaneously integrating other physical cues.

CELL&FORCE offers three main CSSs: devices that allow high-throughput long-term uniaxial (CellTank) or biaxial (Biaxialler) stretching and devices that are microscope-mountable for live-cell imaging (Beatle).

● Max velocity up to 30 mm/s

● Frequency ranges from 0.01-5 Hz

● Ability to program multiple frequency, amplitude and wave changes

● Waveforms available: Static/Sinusoidal/Triangular/Square Heart wave and custom

主站蜘蛛池模板: 哒哒哒高清视频在线观看 | 2021扫黑风暴在线观看免费完整版 | 国产成人高清亚洲一区app | 伊人久久精品AV无码一区 | 高清国产mv视频在线观看 | 日本亚洲精品色婷婷在线影院 | 欧美一区二区在线观看 | 耻辱诊察室1一4集动漫在线观看 | 国产精品高清视亚洲一区二区 | 一个人看的WWW高清电影 | 好湿好滑好硬好爽好深视频 | 葵司中文第一次大战黑人 | 日本一区二区三区在线观看网站 | 国内精品蜜汁乔依琳视频 | 国产亚洲精品久久播放 | 儿媳妇完整版视频播放免费观看 | 精品国产成人系列 | 中国少妇内射XXXX狠干 | 热思思| 亚洲欧美精品无码大片在线观看 | 少女10声大哥喊退色狼 | 色欲精品国产AV久久久 | 9277高清在线观看视频 | 国产精品久久久久婷婷五月色 | 两个人的视频日本在线观看完整 | 暖暖日本手机免费完整版在线观看 | 日本美女搞基视频 | 午夜精品久久久久久影视riav | 1819sextub欧美中国 | 国产69精品久久久久无码麻豆 | 成人免费视频在线 | 超碰97人在线视频 | 美女被触手注入精子强制受孕漫画 | 亚洲精品午夜久久久伊人 | 明星三级电影 | 胸太大被男同桌吃好爽 | 歪歪爽蜜臀AV久久精品人人槡 | 色婷婷AV99XX | 亚洲精品在线观看视频 | 野草观看免费高清视频 | 成人国产AV精品久久久久 |